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Antigenic Specificity | Caspase-8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot (IB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human, mouse, and rat Caspase-8 (18kDa). Caspases are a family of cysteine proteases. Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex. The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain; subsequent oligomerization promotes procaspase-8 autoactivation. FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis. |
Immunogen | Antigen: Synthetic peptide corresponding to 16 amino acids at the C-terminus of human Caspase-8 isoform A (accession no. NP_001219). |
Other Names | [Caspase-8], [CASP8; caspase-8] |
Gene, Accession # | Gene ID: 395284, NCBI: NP_989923.1 |
Catalog # | MBS194502 |
Price | $415 |
Order / More Info | Caspase-8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |