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Antigenic Specificity | CDH5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cadherins are a superfamily of transmembrane glycoproteins that contain cadherin repeats of approximately 100 residues in their extracellular domain. Cadherins mediate calcium-dependent cell-cell adhesion and play critical roles in normal tissue development (1). The classic cadherin subfamily includes N-, P-, R-, B- and E-cadherins, as well as about ten other members that are found in adherens junctions, a cellular structure near the apical surface of polarized epithelial cells. The cytoplasmic domain of classical cadherins interacts with beta-catenin, gamma-catenin (also called plakoglobin), and p120 catenin. beta-catenin and gamma-catenin associate with alpha-catenin, which links the cadherin-catenin complex to the actin cytoskeleton (1,2 |
Immunogen | Immunogen: A synthetic peptide of human CDH5 Calculated Molecular Weight: 88kDa |
Other Names | [VE-Cadherin: CDH5; Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; CD_antigen=CD144; Flags: Precursor], [CDH5; CDH5; 7B4; CD144; VE-cadherin] |
Gene, Accession # | [CDH5], Gene ID: 1003, NCBI: P33151.5, UniProt: P33151 |
Catalog # | MBS125693 |
Price | $200, $275, $430 |
Order / More Info | CDH5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |