Edit |   |
---|---|
Antigenic Specificity | Cytochrome C |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human, rat, rabbit, dog |
Isotype | n/a |
Format | serum |
Size | 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. Defects in CYCS are the cause of thrombocytopenia typ |
Immunogen | Immunogen: Full length recombinant Cytochrome |
Other Names | [cytochrome c; Cytochrome c; cytochrome c; cytochrome c, somatic], [CYCS; CYCS; CYC] |
Gene, Accession # | Gene ID: 475258, NCBI: NP_001183974.1, UniProt: P00011 |
Catalog # | MBS397567 |
Price | $315 |
Order / More Info | Cytochrome C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |