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Antigenic Specificity | PDCD5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDCD5 Antibody: Programmed cell death 5 (PDCD5), a human apoptosis-related protein, is thought to play an early and universal role in apoptosis. PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis, where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 has a compact core structure of low flexibility with two mobile alpha-helices at N-terminal and a flexible unstructured C-terminal region. The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein. PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death. PDCD5 may play a dual role in the Tip60 pathway. It interacts with Tip60 and functions as a Tip60 co-activator to promot |
Immunogen | Immunogen: PDCD5 antibody was raised against a 21 amino acid synthetic peptide from near the carboxy terminus of human PDCD5. Buffer: PDCD5 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PDCD5; DCHT; PASK; SPAK; DCHT; Ste-20-related kinase; serine threonine kinase 39 (STE20/SPS1 homolog, yeast)], [STK39; STK39; DCHT; PASK; SPAK; SPAK; Ste-20-related kinase] |
Gene, Accession # | [STK39], Gene ID: 27347, NCBI: CAG33215, UniProt: Q9UEW8 |
Catalog # | MBS150142 |
Price | $375 |
Order / More Info | PDCD5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |