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Antigenic Specificity | Paxillin |
Clone | [PAX-14] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Monoclonal PXN antibody specific for Human PXN. Biological Significance: Paxillin (PXN) is a signal transduction adaptor protein. The C-terminal region of paxillin contains four LIM domains that target paxillin to focal adhesions. It is presumed through a direct association with the cytoplasmic tail of beta-integrin. The N-terminal region of paxillin is rich in protein protein interaction sites. The proteins that bind to paxillin are diverse and include protein tyrosine kinases, such as Src and focal adhesion kinase (FAK), structural proteins, such as vinculin and actopaxin, and regulators of actin organization, such as COOL/PIX and PKL/GIT.Sequence Info: PXN is composed of 591 amino acids with a molecular weight of 64505 D |
Immunogen | Immunogen: Paxillin antibody was raised in mouse using C-terminal part of recombinant chicken paxillin (amino acids 305-559) as the immunogen |
Other Names | [Mouse Paxillin; Paxillin; Paxillin; Paxillin; PXN; PXN; Paxillin] |
Gene, Accession # | [PXN], Gene ID: 5829, NCBI: P49023.3, UniProt: P49023 |
Catalog # | MBS5309986 |
Price | $345 |
Order / More Info | Paxillin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |