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Antigenic Specificity | SH3PXD2A (N-term), 222-250 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SH3PXD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-250 amino acids from the N-terminal region of human SH3PXD2A. SH3PXD2A is required for podosome formation, degradation of the extracellular matrix, and for the invasiveness of some cancer cells. Binds phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,4-biphosphate (PtdIns(3,4)P2). In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide. |
Immunogen | n/a |
Other Names | [SH3 and PX domain-containing protein 2A; Adapter protein TKS5; Five SH3 domain-containing protein; SH3 multiple domains protein 1; Tyrosine kinase substrate with five SH3 domains; SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5] |
Gene, Accession # | [SH3PXD2A], Gene ID: 9644, NCBI: NP_055446.2, UniProt: Q5TCZ1 |
Catalog # | MBS9202152 |
Price | $165, $370 |
Order / More Info | SH3PXD2A (N-term), 222-250 Antibody from MYBIOSOURCE INC. |
Product Specific References | Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Laumet, G., et al. Neurosci. Lett. 468(1):1-2(2010) Crimaldi, L., et al. Exp. Cell Res. 315(15):2581-2592(2009) Voss, M., et al. BMC Immunol. 10, 53 (2009) : Gianni, D., et al. Sci Signal 2 (88), RA54 (2009) : |