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Antigenic Specificity | Phospho-Akt |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Akt, also referred to as PKB and RAC, is the cellular homologue of the viral oncogene v-Akt. This protein kinase is activated by insulin and various growth factors and functions in a pathway involving PI3 kinase as activation is sensitive to wortmanin. Recent evidence smuggests that Akt functions to promote cell survival by actively inhibiting apoptosis, althomugh the pathways involved have not been identified. Akt is activated by phospholipid binding and phosphorylation within the activation loop at Thr308 and within the C-terminus at Ser473. |
Immunogen | Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser473 of mouse Akt |
Other Names | [RAC serine/threonine-protein kinase; DRAC-PK; Dakt1; DAkt; Protein kinase B; PKB], [AKT1; AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; PKB; RAC; PKB; PKB alpha] |
Gene, Accession # | Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749 |
Catalog # | MBS841206 |
Price | $390 |
Order / More Info | Phospho-Akt Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |