NEIL2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NEIL2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NEIL2 antibody detects endogenous levels of total NEIL2. Function: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'-and 5'-phosphates.Subunit Structure: Binds EP300.Similarity: The zinc-finger domain i |
| Immunogen | Immunogen: A synthesized peptide derived from human NEIL2 Subcellular Location: Nucleus. Tissue Specificity: Detected in testis, skeletal muscle, heart, brain, placenta, lung, pancreas, kidney and liver. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (82%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
| Other Names | [DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease 8-like 2; Endonuclease VIII-like 2; NEH2; Nei endonuclease VIII like 2 (E. coli); Nei endonuclease VIII like 2; Nei homolog 2; Nei-like 2; Nei-like protein 2; NEI2; NEIL2; NEIL2_HUMAN] |
| Gene, Accession # | [NEIL2], Gene ID: 252969, NCBI: NP_001129218.1, UniProt: Q969S2 |
| Catalog # | MBS9609816 |
| Price | $240, $280 |
| Order / More Info | NEIL2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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