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Antigenic Specificity | FK-506 |
Clone | [FK1] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgM |
Format | unconjugated |
Size | 0.2 mg |
Concentration | Ig concentration 1.0mg/ml |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti FK-506 antibody, clone FK1 detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension. |
Immunogen | Immunogen: FK-506-BSA conjugate Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: TRIS buffered saline Target Species: Chemical |
Other Names | n/a |
Gene, Accession # | [FK-506], NCBI: ACA13283.1 |
Catalog # | MBS212926 |
Price | $430 |
Order / More Info | FK-506 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |