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Antigenic Specificity | PRAK |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PRAK antibody detects endogenous levels of total PRAK. Description: PRAK (p38-regulated/activated kinase), also referred to as mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK)-5, is an ubiquitously expressed serine/threonine kinase regulated by p38alpha and p38beta MAP kinases. Activated JNK, p38gamma or p38delta are unable to induce phosphorylation of PRAK in vitro. Phosphorylation of PRAK occurs in vivo in response to p38 activation by stress-related extracellular stimuli including UV light, oxidation and proinflammatory cytokines. Two other substrates for p38, MAPKAPK-2 and MAPKAPK-3/3pK, share approximately 45% sequence homology with PRAK including the phosphorylation motif recognized by p38, Lys-X |
Immunogen | Immunogen: Purified recombinant fragment of human PRAK expressed in E. Coli Subcellular Location: Cytoplasm. Nucleus. Also observed in the nucleus. Tissue Specificity: Expressed ubiquitously. |
Other Names | [MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPK5_HUMAN; MAPKAP kinase 5; MAPKAPK-5; MAPKAPK5; Mitogen activated protein kinase activated protein kinase 5; p38-regulated/activated protein kinase; PRAK] |
Gene, Accession # | [PRAK], Gene ID: 8550, NCBI: NP_003659.2, UniProt: Q8IW41 |
Catalog # | MBS9602716 |
Price | $235, $295, $370 |
Order / More Info | PRAK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |