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Antigenic Specificity | IRS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Insulin receptor substrate 1(IRS1) detection. Tested with WB in Human, Mouse, Rat. Background: Insulin receptor substrate 1(IRS-1) is a signalling adapter protein that in humans is encoded by the IRS-1 gene. It is mapped to 2q36.3. This gene exhibited no intrinsic enzyme activity, and it can serve as a docking protein involved in binding and activating other signal transduction molecules after being phosphorylated on tyrosine by insulin receptor kinase. IRS1 plays a key role in transmitting signals from the insulin and insulin-like growth factor-1(IGF-1) receptors to intracellular pathways PI3K/Akt and Erk MAP kinase pathways. IRS1 also plays important biological function for both metabolic an |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse IRS1 (106-122aa WYQALLQLHNRAKAHHD), identical to the related rat sequence, and different from the related human sequence by one amino acid. |
Other Names | [Insulin receptor substrate 1; insulin receptor substrate 1; HIRS 1; HIRS1; Insulin Receptor Substrate 1;; IRS 1; IRS-1; IRS1; OTTHUMP00000164234], [Irs1; Irs1; G972R; IRS-1; Irs-1; IRS-1] |
Gene, Accession # | [IRS1], Gene ID: 16367, NCBI: P35569.1, UniProt: P35569 |
Catalog # | MBS176893 |
Price | $280 |
Order / More Info | IRS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |