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Antigenic Specificity | Human CD33/Siglec 3 |
Clone | [WM53] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | Protein A purified |
Size | 0.1 mg, 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: CD33, also known as Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67), is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. CD33 binds sialic acids, therefore is a member of the SIGLEC family of lectins. By fluorescence in situ hybridization, CD33 is mapped to 19q13.3-q13.4. Protein Function: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act |
Immunogen | n/a |
Other Names | [Myeloid cell surface antigen CD33; Sialic acid-binding Ig-like lectin 3; Siglec-3; gp67; CD33; CD33; SIGLEC3], [CD33; CD33; p67; SIGLEC3; SIGLEC-3; SIGLEC3; Siglec-3] |
Gene, Accession # | [CD33], Gene ID: 945, NCBI: NP_001076087.1, UniProt: P20138 |
Catalog # | MBS178965 |
Price | $190, $550 |
Order / More Info | Human CD33/Siglec 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |