Akirin2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAkirin2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionAkirin2 Antibody: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-κB-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-κB pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-α and IL-1β signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin
ImmunogenImmunogen: Akirin2 antibody was raised against a 15 amino acid synthetic peptide near the center of the human Akirin2. Buffer: Akirin2 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Akirin2; FBI1; C6orf166; dJ486L4.2; Akirin-2; akirin 2], [AKIRIN2; AKIRIN2; FBI1; C6orf166; dJ486L4.2; C6orf166]
Gene, Accession #[AKIRIN2], Gene ID: 55122, NCBI: EAW48578, UniProt: Q53H80
Catalog #MBS151488
Price$375
Order / More InfoAkirin2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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