Mouse CD86 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD86 |
| Clone | [PO3] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2b |
| Format | fluorescein (FITC) conjugate |
| Size | 0.1 mg |
| Concentration | IgG concentration 0.1 mg/ml |
| Applications | Flow cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti mouse CD86 recognizes mouse CD86 (B7-2), an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse CD86 is expressed at high levels on peripheral blood monocytes and dendritic cells, and at low levels on resting B and T-lymphocytes. Expression of CD86, on these cell populations, can be increased upon activation. CD86 has been identified, along with CD80 (B7-1), as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses. The PO3 antibody has been reported to block some co-stimulatory f |
| Immunogen | Immunogen: Mouse B-cell line, BCL1. Fusion Partners: Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3U1 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [T-lymphocyte activation antigen CD86; T-lymphocyte activation antigen CD86; T-lymphocyte activation antigen CD86; activation B7-2 antigen; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; CD86 antigen; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1; CD_antigen: CD86], [Cd86; Cd86; B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS/A-2; ETC-1] |
| Gene, Accession # | [CD86], Gene ID: 12524, NCBI: NP_062261.3, UniProt: P42082 |
| Catalog # | MBS210978 |
| Price | $370 |
| Order / More Info | Mouse CD86 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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