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Antigenic Specificity | Human CD272 |
Clone | [MIH26] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD272 antibody, clone MIH26 detects human CD272, also known as B- and T-lymphocyte attenuator (BTLA). CD272 is a type I transmembrane glycoprotein which is structurally and functionally related to cytotoxic T lymphocyte antigen-4 (CTLA-4), and programmed death-1 (PD-1). CD272 is a T-cell inhibitory receptor that regulates T cell activation through its interaction with herpes virus entry mediator (HVEM), a co-stimulator receptor of the TNFR family. CD272 may negatively regulate T-cell dependent autoimmune reaction, and polymorphisms in its gene have been associated with Rheumatoid Arthritis. |
Immunogen | Immunogen: BTLA - transfected L cells. Histology Positive Control Tissue: Human tonsil. Fusion Partners: Spleen cells from immunised C3H/HeN mice were fused with cells of the P3U1 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [B- and T-lymphocyte attenuator isoform 2; B- and T-lymphocyte attenuator; B- and T-lymphocyte attenuator; B and T lymphocyte attenuator; B- and T-lymphocyte-associated protein; B and T lymphocyte associated; B- and T-lymphocyte-associated protein; CD_antigen: CD272], [BTLA; BTLA; BTLA1; CD272] |
Gene, Accession # | [CD272], Gene ID: 151888, NCBI: NP_001078826.1, UniProt: Q7Z6A9 |
Catalog # | MBS216280 |
Price | $300 |
Order / More Info | Human CD272 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |