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Antigenic Specificity | CCR5 (NT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-CCR5 (NT) [Rabbit antibody to peptide corresponding to aa 6-20 of human CCR5.]. This antibody recognizes human CCR5 (40 kD). Human immunodeficiency virus (HIV) and related viruses require coreceptors in addition to CD4 to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, CCR8, GPR15, Bonzo, GPR1, and V28, have been identified as HIV coreceptors. Among them, CCR5 is a principal coreceptor for macrophageand dual-tropic HIV-1 strains. CCR5 is required for infection by HIV-1, HIV-2, and SIV. The beta -chemokines RANTES, MIP-1 alpha , and MIP-1 beta are the ligands for CCR5 and prevent infection by macrophage-tropic HIV-1. CCR5 associates with the surface CD4-gp120 of HIV complex and lead |
Immunogen | Antigen: Peptide corresponding to aa 6-20 of human CCR5. |
Other Names | n/a |
Gene, Accession # | NCBI: ACL97978.1 |
Catalog # | MBS194047 |
Price | $415 |
Order / More Info | CCR5 (NT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |