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Antigenic Specificity | NCBP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation wh |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-156 of human NCBP2 (NP 031388.2). |
Other Names | [CBC2; NIP1; CBP20; PIG55] |
Gene, Accession # | [NCBP2], Gene ID: 22916, NCBI: NP_001036005.1, UniProt: P52298 |
Catalog # | MBS8546711 |
Price | $280 |
Order / More Info | NCBP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |