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Antigenic Specificity | Cleaved PARP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly (ADP-ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. With EEF1A1 and TXK, forms a complex that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytok |
Immunogen | Immunogen: A synthesized peptide derived from human Cleaved PARP. Sensitivity: Cleaved PARP Antibody detects endogenous levels of total Cleaved PARP |
Other Names | [ADPRT; ADP-Ribosyltransferase; CPP32; PARP; PARP1; SCA1; PPOL; YAMA], [PARP1; PARP1; PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1; ADPRT; PPOL; PARP-1; ARTD1; ADPRT 1] |
Gene, Accession # | Gene ID: 142, NCBI: NP_001609.2, UniProt: P09874 |
Catalog # | MBS477168 |
Price | $335 |
Order / More Info | Cleaved PARP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |