Edit |   |
---|---|
Antigenic Specificity | IFN-alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IFN-alpha antibody detects endogenous levels of total IFN-alpha. Description: Interferon-alpha1 is a member of the Type I IFN (1) family best known for their antiviral activity. Most nucleated cells produce one or more Type I IFNs in response to viral infection (2). Secreted Type I IFN then induces viral protective responses in neighboring non-infected cells. Type I IFNs also enhance virus-induced apoptosis (3). Other IFN-alpha1 activities include enhancement of dendritic cell maturation and cytotoxic T cell activity (4). IFN-alpha1 binds to the IFN-alphaR1 and IFN-alphaR2 heterodimer (1). Intracellular signaling through the Jak/Stat pathway is best characterized (3). However, the PI3K, ERK, and p38 kinase pathways are also inv |
Immunogen | Immunogen: A synthesized peptide derived from human IFN-alpha Subcellular Location: Secreted. Predicted Cross Reactivity: Pig Similarity: Pig (88%) |
Other Names | [IFL; IFN alpha; IFN alpha 1/13; IFN alpha 1b; IFN alphaD; IFN; IFN-alpha-1/13; IFNA; IFNA1; IFNA1_HUMAN; IFNA13; Interferon alpha 1; Interferon alpha-1/13; Interferon alpha-D; Interferon alpha1; Interferon, alpha 13; LeIF D] |
Gene, Accession # | [IFN-alpha], Gene ID: 3447, NCBI: NP_008831.3, UniProt: P01562 |
Catalog # | MBS9606747 |
Price | $240, $280 |
Order / More Info | IFN-alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |