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Antigenic Specificity | KCa2.3 (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rat, mouse, pig-identical. Small conductance calcium-activated potassium channel, KCa3, Kcnn3, SKCa3 KCa2.3 is a member of the Ca2+-activated K+ channels family with small conductance that includes KCa2.1 (SK1) and KCa2.2 (SK2). The channel is voltage insensitive and is activated by intracellular Ca2+ in the submicromolar range. It has, though, a similar topology to that of voltage-dependent K+ channels (Kv channels), that is six transmembrane domains and intracellular N-and C-termini. The functional channel of all the KCa2 family members is a multimeric protein composed of four pore-forming subunits. KCa2 channels are extremely sensitive to the levels of intracellular Ca2+ and concentrations as low as 300-700 nM can open the c |
Immunogen | Immunogen: Peptide DTSGHFHDSGVGDLDEDPKC, corresponding to amino acid residues 2-21 of human KCa2.3 (SK3) (Accession NP 002240). |
Other Names | [K Ca2-3] |
Gene, Accession # | [KCa2.3] |
Catalog # | MBS4159223 |
Price | $725 |
Order / More Info | KCa2.3 (N-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |