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Antigenic Specificity | Human BUB1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | n/a |
Immunogen | Immunogen: Recombinant protein of human BUB1B. Relevance: The Mitotic Checkpoint Complex (MCC), which contains Bub1, Bub1b, Bub3, Mad2, and Cdc20, controls chromosome segregation and monitors kinetochore-microtubule interactions. During mitosis, the MCC complex inhibits the ubiquitin ligase activity of the Anaphase Promoting Complex/Cyclosome (APC/C), thereby preventing cells with unaligned chromosomes from prematurely entering anaphase. Research studies have shown that Bub1b and Bub1 kinases ar |
Other Names | [Bub1b; BUB1beta; BUBR1; Bub1A; MAD3L; SSK1; hBUBR1], [BUB1B] |
Gene, Accession # | [BUB1B], NCBI: ADF57218.1 |
Catalog # | MBS1490473 |
Price | $295 |
Order / More Info | Human BUB1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |