Edit |   |
---|---|
Antigenic Specificity | Phospho-PRKCZ (T560) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium-and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory response and maintenance of long-term potentiation (LTP). Upon lipopolysaccharide (LPS) treatment in macrophages, or following mitogenic stimuli, functions downstream of PI3K to activate MAP2K1/MEK1-MAPK1/ERK2 signaling cascade independently of RAF1 activation. Required for insulin-dependent activation of AKT3, but may function as an adapter rather than a direct activator. Upon insulin treatment may act as a downstream effector of PI3K and contribut |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-PRKCZ (T560) |
Other Names | [Protein kinase C zeta type; nPKC-zeta; PRKCZ; PKC2] |
Gene, Accession # | [PRKCZ], Gene ID: 5590, NCBI: NP_001028753.1, UniProt: Q05513 |
Catalog # | MBS7114883 |
Price | $185, $265 |
Order / More Info | Phospho-PRKCZ (T560) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |