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Antigenic Specificity | NOXA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises murine Noxa, an 11kDa member of the BH3-only proapoptotic protein family. Noxa is localised to the mitochondria and is a transcriptional target of p73, p53 and BH3-only proteins. It is thought to induce apoptosis when activated, lowering the activity of anti-apoptotic Bcl-2-like proteins. It can be upregulated by mitogenic activation, independently of p53. In humans, along with Mcl-1 it is thought to form a selective pathway that restrains lymphocyte proliferation. MBS221324 recognises murine Noxa, an 11kDa member of the BH3-only proapoptotic protein family. Noxa is localised to the mitochondria and is a transcriptional target of p73, p53 and BH3-only proteins. It is thought to induce apoptosis when activated, lowering |
Immunogen | Immunogen: Synthetic peptide corresponding to N-terminus of mouse NOXA. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to NOXA were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Mouse |
Other Names | [phorbol-12-myristate-13-acetate-induced protein 1; Phorbol-12-myristate-13-acetate-induced protein 1; phorbol-12-myristate-13-acetate-induced protein 1; protein Noxa; phorbol-12-myristate-13-acetate-induced protein 1; Protein Noxa], [Pmaip1; Pmaip1; Noxa; Noxa] |
Gene, Accession # | [NOXA], Gene ID: 58801, NCBI: NP_067426.1, UniProt: Q9JM54 |
Catalog # | MBS221324 |
Price | $375 |
Order / More Info | NOXA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |