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Antigenic Specificity | GMNN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GMNN antibody detects endogenous levels of total GMNN. Description: This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene ar |
Immunogen | Immunogen: A synthesized peptide derived from human GMNN Subcellular Location: Nucleus Tissue Specificity: Absent during G1 phase, accumulates during S, G2, and M phases, and disappears at the time of the metaphase-anaphase transition. Predicted Cross Reactivity: Pig, Rabbit Similarity: Pig (80%), Rabbit (80%) |
Other Names | [DNA replication inhibitor; Gem; GEMI_HUMAN; Geminin; Geminin DNA replication inhibitor; GMNN; OTTHUMP00000039393; RP3 369A17.3] |
Gene, Accession # | [GMNN], Gene ID: 51053, NCBI: NP_001238918.1, UniProt: O75496 |
Catalog # | MBS9607908 |
Price | $240, $280 |
Order / More Info | GMNN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |