Caspase-8 (Active) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Caspase-8 (Active) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg |
| Concentration | 0.5 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Caspase-8, a member of the caspase-family of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase-8 is synthesized as inactive pro-enzyme and activation of the enzyme involves proteolytic cleavage that leads to the release of the active p18 and p10 subunits. Activated caspase-8 is able to cleave and activate downstream caspases, such as caspase-3, -6, -7 and a death agonist member of the Bcl-2/Bcl-xL family, Bid, leading to apoptosis. |
| Immunogen | Immunogen: Synthetic peptide corresponding to residues surrounding amino acid 392 of mouse caspase-8 |
| Other Names | [CASP8; MGC78473; CASP-8; MACH; procaspase-8; MCH5; ALPS2B; FLICE; CAP4; EC 3.4.22.61], [Casp8; Casp8; MACH; Mch5; FLICE; CASP-8; CASP-8] |
| Gene, Accession # | Gene ID: 12370, NCBI: BC006737 |
| Catalog # | MBS840992 |
| Price | $150, $305 |
| Order / More Info | Caspase-8 (Active) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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