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Antigenic Specificity | M3K12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of M3K12 protein. MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12) encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described. MAP3K12 |
Immunogen | Immunogen: Synthesized peptide derived from part region of human M3K12 protein at amino acid sequence of 730-810 |
Other Names | [Rabbit M3K12; JNK-associated leucine-zipper protein; JLP; Mitogen-activated protein kinase 8-interacting protein 4; Proliferation-inducing protein 6; Protein highly expressed in testis; PHET; Sperm surface protein; Sperm-associated antigen 9; Sperm-specific protein; Sunday driver 1] |
Gene, Accession # | [M3K12], Gene ID: 7786, NCBI: NP_006292.3, UniProt: Q12852 |
Catalog # | MBS9709733 |
Price | $130, $220, $325 |
Order / More Info | M3K12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |