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Antigenic Specificity | SHB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SHB protein. Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.Welsh M., Oncogene 9:19-27(1994).Humphray S.J., Nature 429:369-374(2004).Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human SHB. |
Other Names | [SH2 domain-containing adapter protein B; SHB] |
Gene, Accession # | [SHB], Gene ID: 6461, NCBI: NP_003019.2, UniProt: Q15464 |
Catalog # | MBS9409129 |
Price | $200, $255 |
Order / More Info | SHB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |