Mouse VEGFR-2/Flk-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse VEGFR-2/Flk-1 |
| Clone | polyclonal |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody will detect native human VEGFR-2/KDR on the surface of different human cell types. VEGF R2 (mouseFlk1 gene), VEGF R1 (Flt1) and VEGF R3 (Flt4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulinlike repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGF R1, 2, and 3 is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis. Mouse VEGF R2 cDNA encodes a 1367 amino acid (aa) precursor protein with a 19 aa signal peptide. Mature VEGF R2 is composed of a 743 aa extracellular domain, a 22 aa transmembrane domain, and |
| Immunogen | Immunogen: recombinant mouse soluble Flk-1. Preparation: Monoclonal antibodies were produced with the help of BALB/c mice using recombinant mouse soluble extracellular Flk-1 as the immunizing antigen |
| Other Names | [mouse VEGFR-2/Flk-1 (#3C8); Vascular endothelial growth factor receptor 2], [Kdr; Kdr; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07; Flk-1; Flk1; VEGFR-2; FLK-1] |
| Gene, Accession # | [VEGFR-2/Flk-1], Gene ID: 16542, NCBI: ACJ66293.1, UniProt: P35918 |
| Catalog # | MBS690186 |
| Price | $345 |
| Order / More Info | Mouse VEGFR-2/Flk-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Shibata et al, BMC Medicine 8 (2010) 2. Albaquerque et al, Nature Med 2009 3. Ebos et al, Mol Cancer Res 2 (2004) 4. Ebos et al, Cancer res 68 (2008). 5. Benzinger et al., BBA 1466:71, 2000 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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