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Antigenic Specificity | Tyrosine Kinase Receptor C (TrkC) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specificity was demonstrated by immunohistochemistry. This antibody was used to stain cryostat sections of the rat peripheral sensory ganglia. TrkC is a member of the neurotrophic tyrosine receptor kinase family. TrkC is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkC is the receptor for neurotrophin-3 (NT-3). Signalling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein. ALTERNATIVE products_recove |
Immunogen | Immunogen: Extracellular domain of glycosylated human TrkC protein produced in CHO cells was used as the immunogen. Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide. |
Other Names | [TRKC; NT-3 growth factor receptor; NT-3 growth factor receptor; neurotrophic receptor tyrosine kinase 3; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase] |
Gene, Accession # | [TrkC], Gene ID: 4916, NCBI: CAA12029.1, UniProt: Q16288 |
Catalog # | MBS4152728 |
Price | $515 |
Order / More Info | Tyrosine Kinase Receptor C (TrkC) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |