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Antigenic Specificity | 4E-BP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |
Immunogen | Immunogen: 4E-BP1 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of threonine 45 (S-T-T(p)-P-G) derived from Human 4E-BP1 as the immunogen. |
Other Names | [Rabbit 4E-BP1; 4E-BP1; 4E-BP1; Eukaryotic translation initiation factor 4E-binding protein 1; E-BP1-4; E-BP1 4; E-BP1-4; Phospho Thr45; 4E-BP1; E-BP1 4] |
Gene, Accession # | [4E-BP1], Gene ID: 100861234, NCBI: AEM43813.1 |
Catalog # | MBS5309581 |
Price | $295 |
Order / More Info | 4E-BP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |