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Antigenic Specificity | CD56(NCAM) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NCAM protein. NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains (1). NCAM mediates neuronal attachment, neurite extension and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma and rhabdomyosarcoma (2). CD56 and CD16 are commonly used to identify NK cells although some cells with the T cell markers CD3 and CD4 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.850~854(Q-T-K-E-N)derived from Human CD56(NCAM). |
Other Names | [MSK39; NCAM1] |
Gene, Accession # | [CD56], Gene ID: 4684, NCBI: NP_000606.3, UniProt: P13591 |
Catalog # | MBS9404502 |
Price | $200, $255 |
Order / More Info | CD56(NCAM) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |