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Antigenic Specificity | Rho (pS188) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | 100 ug/200 ul |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~24 kDa of human RhoA protein. It also reacts with mouse and rat. The other species are not tested. Ras homolog gene family consists of RhoA, RhoB, RhoC proteins. These proteins interact directly with protein kinase (Rho kinase) to serve as downstream effectors of the activated GTPase. The Rho proteins are involved in the regulation of the actin cytosekeleton. Activation of Rho to the GTP bound state promotes formation of stress fibers and is required for the formation and maintenance of focal adhesions. Pathways stimulated by cytokines, hormones and various forms of stress utilize p21 proteins of the Rho family2. Possible mediators for these responses include protein kinase such as p120PKN, and p150, ROK alpha /Rho |
Immunogen | Antigen Preparation: A synthetic peptide corresponding to the C-term of epitope KKKSG at a phosphorylation Ser188 of human Rho protein |
Other Names | [Rabbit Rho (pS188) Phospho-specific; Ras homolog gene family; member A variant (RhoA); ARHA; RhoH12,], [rho] |
Gene, Accession # | [Rho], Gene ID: 8893956 |
Catalog # | MBS462121 |
Price | $285 |
Order / More Info | Rho (pS188) Antibody from MYBIOSOURCE INC. |
Product Specific References | • Zavzavadjian,J.R, Mol. Cell Proteomics 6 (3), 413-424 (2007) |