MCL1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-MCL1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | MCL1 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | Protein A purified |
| Size | 0.06 mL, 0.12 mL, 0.2 mL |
| Concentration | 1mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MCL-1 is an anti-apoptotic member of the Bcl-2 family originally isolated from the ML-1 human myeloid leukemia cell line. Similar to BCL2 and BCL2L1, MCL1 can interact with BAX and/or BAK1 to inhibit mitochondria-mediated apoptosis. Mcl-1 is critical for the proliferation and survival of myeloma cells in vitro, and overexpression of Mcl-1 protein in myeloma cells is associated with relapse and short event-free survival in multiple myeloma patients. Recent studies show that MCL-1 is upregulated in numerous haematological and solid tumour malignancies. Therefore, MCL-1 has been suggested as a potential new therapeutic target. |
| Immunogen | Immunogen: MCL1 fusion protein ag10609 |
| Other Names | [EAT; Mcl 1; Mcl 1l; Mcl 1s Delta TM; MCL1; mcl1/EAT; MCL1L; MCL1S; TM] |
| Gene, Accession # | [MCL1], Gene ID: 4170, NCBI: NP_001184249.1, UniProt: Q07820 |
| Catalog # | MBS2540210 |
| Price | $220, $290, $435 |
| Order / More Info | MCL1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies