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Antigenic Specificity | Phospho-TrkA (Y791) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.43 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TrkA Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y791 of human TrkA. TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. |
Immunogen | n/a |
Other Names | [High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A; Trk-A; gp140trk; p140-TrkA; NTRK1; MTC; TRK; TRKA] |
Gene, Accession # | [NTRK1], Gene ID: 4914, NCBI: NP_001007793.1, UniProt: P04629 |
Catalog # | MBS9202385 |
Price | $165, $370 |
Order / More Info | Phospho-TrkA (Y791) Antibody from MYBIOSOURCE INC. |
Product Specific References | Tokusashi, Y., et al., Int. J. Cancer 114(1):39-45 (2005). Schulte, J.H., et al., Oncogene 24(1):165-177 (2005). Frattini, M., et al., Oncogene 23(44):7436-7440 (2004). Tacconelli, A., et al., Cancer Cell 6(4):347-360 (2004). Florenes, V.A., et al., Am. J. Clin. Pathol. 122(3):412-420 (2004). |