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Antigenic Specificity | GPR144 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GPR144 Polyclonal Antibody detects endogenous levels of GPR144 protein. G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotection by reducing cardiac hypertroph |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human GPR144 at AA rangle: 60-140 |
Other Names | [Rabbit GPR144; GPR144; PGR24; Probable G-protein coupled receptor 144; G-protein coupled receptor PGR24] |
Gene, Accession # | [GPR144], Gene ID: 347088, NCBI: NP_001155280.1, UniProt: Q7Z7M1 |
Catalog # | MBS9705481 |
Price | $130, $220, $325 |
Order / More Info | GPR144 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |