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Antigenic Specificity | p90 RSK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, bovine |
Isotype | n/a |
Format | APC-Cy7 conjugate |
Size | 0.4 mL |
Concentration | 0.25 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~90 kDa. The p90 ribosomal S6 kinase (Rsk) family comprises four mammalian serine/threonine kinases (Rsk1-4). In the past, S6K1 and S6K2 were thought to be the predominant operating S6 kinases, however RSK 1 and 2 have been shown to phosphorylate S6 in response to the ERK pathway, or otherwise known as the extra cellular signal-regulated kinases pathway. RSK 1 in particular is very multifunctional as it participates in nuclear signaling, regulates nuclear factors, regulates several transcription factors like c-Fos, and interacts with the transcriptional coactivator CREB-binding protein. As a result, RSK1 seems to have an important role in cellular growth control and proliferation. (1-5). |
Immunogen | Immunogen: Human p90 RSK1 C-terminal peptide, conjugated to KLH |
Other Names | [Rabbit Human p90 RSK1; p90RSK; RSK1; RPS6KA1; p90 RSK1; MAPKAPK-1a; p90S6K; Ribosomal S6 kinase 1; RSK1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; EC:2.7.11.1; p90-RSK 1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; p90RSK1; 90 kDa ribosomal protein S6 kinase 1; RSK-1; MAPKAP kinase 1a; MAPKAPK1A] |
Gene, Accession # | [RSK1], Gene ID: 6195, NCBI: NP_001006666.1, UniProt: Q15418 |
Catalog # | MBS8004199 |
Price | $395 |
Order / More Info | p90 RSK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Roux, P. (2007). UCSD-Nature Molecule Pages. 2. Fro din, M. and Gammeltoft, S. (1999) Mol. Cell. Endocrinol. 151: 65-77. 3. Merienne, K. et al. (1998) J. Med. Genet. 35: 890-894. 4. De Cesare, D. et al. (1998) Proc. Natl. Acad. Sci. 95: 12202-12207. 5. Joel, P. B. et al. (1998) Mol. Cell. Biol. 18: 1978-1984. |