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Antigenic Specificity | PBR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PBR Polyclonal Antibody detects endogenous levels of PBR protein. Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by TSPO (translocator protein) interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human PBR at AA range: 90-170 |
Other Names | [Rabbit PBR; TSPO; BZRP; MBR; Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR] |
Gene, Accession # | [PBR], Gene ID: 706, NCBI: NP_001243460.1, UniProt: P30536 |
Catalog # | MBS9707012 |
Price | $130, $220, $325 |
Order / More Info | PBR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |