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Antigenic Specificity | Phospho-eEF2k (Ser366) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Phospho-eEF2k (Ser366) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 337-371 amino acids from the human region of human EEF2k. Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. |
Immunogen | n/a |
Other Names | [Eukaryotic elongation factor 2 kinase; eEF-2 kinase; eEF-2K; 2.7.11.20; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; EEF2K] |
Gene, Accession # | [EEF2K], Gene ID: 29904, NCBI: NP_037434.1, UniProt: O00418 |
Catalog # | MBS9231108 |
Price | $165, $370 |
Order / More Info | Phospho-eEF2k (Ser366) Antibody from MYBIOSOURCE INC. |
Product Specific References | Ryazanov A.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:4884-4889 (1997). Martin J.,et al.Nature 432:988-994 (2004). Pavur K.S.,et al.Biochemistry 39:12216-12224 (2000). Knebel A.,et al.EMBO J. 20:4360-4369 (2001). Wang X.,et al.EMBO J. 20:4370-4379 (2001). |