Edit |   |
---|---|
Antigenic Specificity | ATP6V0D1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human ATP6V0D1 (NP 004682.2). |
Other Names | [P39; VATX; VMA6; ATP6D; ATP6DV; VPATPD] |
Gene, Accession # | [ATP6V0D1], Gene ID: 9114, NCBI: P61421.1, UniProt: P61421 |
Catalog # | MBS8545355 |
Price | $280 |
Order / More Info | ATP6V0D1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |