ECRG2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ECRG2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ECRG2 antibody is predicted to not cross-react with other ECRG family members. The esophageal cancer-susceptibility gene 2 (ECRG2), also known as SPINK7, is a novel tumor suppressor gene identified from the human esophagus. It interacts directly with metallothionein 2A and urokinase-type plasminogen activator (uPA), and downregulates the activity of uPA, leading to reduced cancer cell migration, invasion and metastasis. ECRG2 forms a complex with uPA and its receptor uPAR, modifying the dynamic association of uPAR with beta1 integrins and disrupting the Src/MAP kinase pathway that normally stimulates cell migration and invasion. ECRG2 may thus represent a novel therapeutic target for cancer. |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide near the carboxy terminus of human ECRG2. |
| Other Names | [Esophageal cancer-susceptibility gene 2 protein, ECG2, serine protease inhibitor Kazal-type 7; SPINK7] |
| Gene, Accession # | [ECRG2], Gene ID: 84651, NCBI: AAI09386 |
| Catalog # | MBS9404664 |
| Price | $320 |
| Order / More Info | ECRG2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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