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Antigenic Specificity | p62dok |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-DOK (CT) [Rabbit antibody to peptide corresponding to aa 425-439 of human p62dok.]. This antibody recognizes human p62dok (62kD). Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptor tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates which mediates the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF, and insulin receptors, has been identified in human and mouse. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok, along wi |
Immunogen | Antigen: Peptide corresponding to aa 425-439 of human p62dok. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS194125 |
Price | $415 |
Order / More Info | p62dok Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |