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Antigenic Specificity | Jagged 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Jagged belongs to the Delta-Serrate-Lag-2 (DSL) family of ligands that activate LIN12/Notch proteins. Ligands for Notch include Jagged1, Jagged2 and Delta. Jagged 1is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis. Mutation in Jagged1 is associated with an autosomal dominant disorder known as Alagille syndrome and Familial Tetralogy of Fallot a form of complex congenital heart disease. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 114 of rat Jagged 1. Positive Control: 3T3 cell lysate |
Other Names | [CD339], [Jag1; Jag1; Jagged1] |
Gene, Accession # | Gene ID: 29146, NCBI: NP_062020.1, UniProt: Q63722 |
Catalog # | MBS840822 |
Price | $150, $290 |
Order / More Info | Jagged 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |