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Antigenic Specificity | KCNJ11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total KCNJ11 protein. Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant no |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human KCNJ11. |
Other Names | [BIR; HHF2; PHHI; IKATP; TNDM3] |
Gene, Accession # | [KCNJ11], Gene ID: 3767, NCBI: NP_001159762.1, UniProt: Q14654 |
Catalog # | MBS9412678 |
Price | $255 |
Order / More Info | KCNJ11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |