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Antigenic Specificity | BAK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, human |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human BAK is a 211 amino acid protein. The Bcl-2 family of apoptosis-related genes plays central roles in regulating apoptotic pathways. Bcl-2 family proteins can be divided into 3 main subfamilies on the basis of their function and the content of their Bcl-2 homology (BH) domains, for example: 1) Prosurvival: Bcl-2, Bcl-XL, Bcl-W, A1, and Mcl-1 2) Proapoptotic (multidomain): Bax, Bak, and Bok. 3) BH3-only (proapoptotic): Bad, Bcl-XS, Bid, Bik, Bim, Blk, Bmf, Bnip, Noxa, and Puma. Regulation of cell death through apoptosis is critical for the maintenance of homeostasis, defense against infectious agents, and normal development. Bcl-2 family proteins regulate apoptosis primarily through the regulation of mitochondrial outer membrane permeabi |
Immunogen | Immunogen Information: A synthetic peptide of BAK protein (amino acids 16-36 EPALPSASEEQVAQDTEEVFR) was used as the immunogen for this antibody |
Other Names | [BAK1; BAK; BCL2L7; CDN1; Apoptosis regulator BAK; Bcl2-L-7; Bcl-2-like protein 7; to BAK; BAK; BAK], [BAK1; BAK1; BAK; CDN1; BCL2L7; BAK-LIKE; BAK; BCL2L7; CDN1; Bcl2-L-7] |
Gene, Accession # | [BAK1], Gene ID: 578, NCBI: Q16611.1, UniProt: Q16611 |
Catalog # | MBS668530 |
Price | $270 |
Order / More Info | BAK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |