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Antigenic Specificity | CD27 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD27 antibody detects endogenous levels of total CD27. Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]Function: |
Immunogen | Immunogen: A synthesized peptide derived from human CD27 Subcellular Location: Membrane. Tissue Specificity: Found in most T-lymphocytes. Predicted Cross Reactivity: Bovine, Horse, Sheep Similarity: Bovine (86%), Horse (86%), Sheep (86%) |
Other Names | [CD 27; Cd27; CD27 antigen; CD27 molecule; CD27_HUMAN; CD27L receptor; LPFS2; MGC20393; OTTHUMP00000238557; S152; T cell activation antigen CD27; T cell antivation antigen S152; T-cell activation antigen CD27; T14; TNFRSF 7; TNFRSF7; TNFSF7; Tp 55; Tp55; Tumor necrosis factor receptor superfamily member 7] |
Gene, Accession # | [CD27], Gene ID: 939, NCBI: NP_001233.1, UniProt: P26842 |
Catalog # | MBS9607365 |
Price | $240, $280 |
Order / More Info | CD27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |