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Antigenic Specificity | MEK7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MEK7 Antibody detects endogenous levels of MEK7. MKK7 is strongly activated by TNF-alpha, as well as other environmental stresses, whereas SEK1/MKK4, which activates both p38 and SAPK/JNK pathways, is not activated by TNF-alpha. Sequence alignment of the activation loop of the MAP kinase kinase family members indicates that Ser271 and Thr275 are potential phosphorylation sites that are crucial for the kinase acivity. |
Immunogen | Immunogen: A synthesized peptide derived from human MEK7 |
Other Names | [MKK7; Jnkk2; MAPKK7; PRKMK7; JNK-activating kinase 2; MAPKK 7; Mitogen Activated Protein Kinase kinase 7; SAPKK4; stress-activated protein kinase kinase 4] |
Gene, Accession # | [MEK7], Gene ID: 5609, NCBI: NP_001284484.1, UniProt: O14733 |
Catalog # | MBS4750594 |
Price | $335 |
Order / More Info | MEK7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |