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Antigenic Specificity | CD8b |
Clone | [341] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | affinity purified |
Size | 0.05 mg |
Concentration | 500 ug/ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 341 monoclonal antibody reacts with rat CD8beta. CD8beta is a member of the immunoglobulin superfamily which heterodimerizes with CD8 alpha to form the CD8 antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class I-restricted peripheral T cells, and on some macrophages. CD8beta expression is absent in athymic mice, which are populated by T-cells expressing CD8 alpha homodimers. This has led to the idea that CD8beta expression is dependent on the development of T cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting cells during antigen presentation, and participates in T-cell receptor signal transduction through association with the kinase Lck. |
Immunogen | n/a |
Other Names | [Mouse CD8b; CD8b; CD8b; CD8 beta; CD-8b; CD-8b; CD 8b; CD8b; CD 8b; Ly-3] |
Gene, Accession # | [CD8b], Gene ID: 926, NCBI: AAI00912.1 |
Catalog # | MBS5309222 |
Price | $170 |
Order / More Info | CD8b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |