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Antigenic Specificity | AUP1 (C-term), 440-468 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This AUP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the C-terminal region of human AUP1. This gene encodes a protein that contains a domain withhomology to the ancient conserved region of the archain 1 gene anda domain that may be involved in binding ubiquitin-conjugatingenzymes. The protein encoded by this gene has been shown to bind tothe conserved membrane-proximal sequence of the cytoplasmic tail ofintegrin alpha(IIb) subunits. These subunits play a crucial role inthe integrin alpha(IIb)beta(3) inside-out signalling in plateletsand megakaryocytes that leads to platelet aggregation and thrombusformation. This gene overlaps the gene |
Immunogen | n/a |
Other Names | [Ancient ubiquitous protein 1; AUP1] |
Gene, Accession # | [AUP1], Gene ID: 550, NCBI: NP_853553.1, UniProt: Q9Y679 |
Catalog # | MBS9209194 |
Price | $165, $370 |
Order / More Info | AUP1 (C-term), 440-468 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Kato, A., et al. J. Biol. Chem. 277(32):28934-28941(2002) Karpisheva, K.V., et al. Tsitologiia 44(9):846-851(2002) Karpisheva, K.V., et al. Tsitologiia 44(9):839-845(2002) Jang, W., et al. Genomics 36(2):366-368(1996) |