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Antigenic Specificity | Smad5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGF beta/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF and activin mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGF beta signaling by interfering with TGF beta mediated phosphorylation of other Smad family members. |
Immunogen | Immunogen: Smad5 antibody was raised in Rabbit using synthetic peptide corresponding to amino acids residues around 252 of human Smad5 as the immunogen. |
Other Names | [Rabbit Smad5; Smad5; Smad5; Smad-5; Smad5; Smad 5; Smad-5; Smad 5; Smad-5] |
Gene, Accession # | [Smad5], Gene ID: 4090, NCBI: AAB92396.1 |
Catalog # | MBS5309115 |
Price | $705 |
Order / More Info | Smad5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |