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Antigenic Specificity | SNX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SNX1 antibody detects endogenous levels of total SNX1. Function: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3, 5-bisphosphate (PtdIns(3, 5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvatur |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Endosome Membrane. Golgi Apparatus > Trans-Golgi Network Membrane. Early Endosome Membrane. Enriched on tubular elements of the early endosome membrane. Binds preferentially to highly curved membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3, 5-bisphosphate (PtdIn. |
Other Names | [HsT17379; MGC8664; SNX 1; SNX 1a; Snx1; SNX1_HUMAN; SNX1A; Sorting nexin 1; Sorting nexin 1A; Sorting nexin-1; Vps5] |
Gene, Accession # | [SNX1], Gene ID: 6642, NCBI: NP_001229862.1, UniProt: Q13596 |
Catalog # | MBS9605990 |
Price | $240, $280 |
Order / More Info | SNX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |